Axon initial segment — Free Physiology Illustration | GPAI | GPAI

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Axon initial segment — Free Physiology Illustration | GPAI | GPAI

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Axon initial segment

Axon initial segment

Physiology

Axon initial segment

Short specialized proximal segment of a neuron at the base of the axon, immediately beyond the axon hillock where the axon emerges from the soma. It appears as a smooth pale extension with a clear transition from the larger cell body into the axon, slightly tapered at its origin and then becoming a short narrow cylindrical first straight section. The segment is narrower than the soma and slightly thicker than the distal axon, with a clean smooth outline and visually distinct as the defined start region of the axon.

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