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Topologically associated domain — Free Biology Illustration | GPAI | GPAI

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Topologically associated domain

Topologically associated domain

Biology

Topologically associated domain

A topologically associated domain shown as a compact, self-contained looping segment of chromatin: a thick flexible purple DNA fiber folded into a distinct rounded lobe or loop with several bundled internal loops and bends, suggesting frequent internal contacts within one discrete structural unit. The domain appears as a compact self-interacting loop within a longer chromatin strand, often with the base of the loop anchored by protein complexes.

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